Estrogen-replacement increases infarct size in ovarlectomized Rats
نویسندگان
چکیده
منابع مشابه
Increases Myocardial Infarct Size in Rats
Background Exposure to environmental tobacco smoke (ETS) has been epidemiologically linked to death from ischemic heart disease in nonsmokers. In this study, we evaluated the influence of 3 days, 3 weeks, and 6 weeks of ETS exposure on myocardial infarct size in a rat ischemia/reperfusion model. Methods and Results Sprague-Dawley rats exposed to ETS (four Marlboro cigarettes per 15 minutes, 6 h...
متن کاملEffects of estrogen replacement on infarct size, cardiac remodeling, and the endothelin system after myocardial infarction in ovariectomized rats.
BACKGROUND Estrogen may increase the long-term survival of women who have suffered from a myocardial infarction (MI). We examined the acute and chronic influence of estrogen on MI in the rat left coronary artery ligation model. METHODS AND RESULTS Female Sprague-Dawley rats (10 to 12 weeks, n=93), divided into 3 groups (rats with intact ovaries, ovariectomized rats administered 17beta-estradi...
متن کامل1282 Exposure to Environmental Tobacco Smoke Increases Myocardial Infarct Size in Rats
Background Exposure to environmental tobacco smoke (ETS) has been epidemiologically linked to death from ischemic heart disease in nonsmokers. In this study, we evaluated the influence of 3 days, 3 weeks, and 6 weeks of ETS exposure on myocardial infarct size in a rat ischemia/reperfusion model. Methods and Results Sprague-Dawley rats exposed to ETS (four Marlboro cigarettes per 15 minutes, 6 h...
متن کاملHuman C-reactive protein increases cerebral infarct size after middle cerebral artery occlusion in adult rats.
Human C-reactive protein (CRP), the classic acute phase plasma protein, increases in concentration after myocardial infarction and stroke. Human CRP binds to ligands exposed in damaged tissue and can then activate complement and its proinflammatory functions. In contrast, rat CRP, which binds to similar ligands, does not activate complement. In the present study, systemic complement depletion w...
متن کاملExposure to environmental tobacco smoke increases myocardial infarct size in rats.
BACKGROUND Exposure to environmental tobacco smoke (ETS) has been epidemiologically linked to death from ischemic heart disease in nonsmokers. In this study, we evaluated the influence of 3 days, 3 weeks, and 6 weeks of ETS exposure on myocardial infarct size in a rat ischemia/reperfusion model. METHODS AND RESULTS Sprague-Dawley rats exposed to ETS (four Marlboro cigarettes per 15 minutes, 6...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1998
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(98)80119-8